Today’s Topic in Focus: Time-Restricted Eating [05:14]
- Lowe et al., 2020 – TREAT RCT
- Sutton et al., 2018 – Early Time-Restricted Feeding Improves Insulin Sensitivity, Blood Pressure, and Oxidative Stress Even without Weight Loss in Men with Prediabetes
- Hutchinson et al., 2019 – Time‐Restricted Feeding Improves Glucose Tolerance in Men at Risk for Type 2 Diabetes: A Randomized Crossover Trial
- Gabel et al., 2018 – Effects of 8-hour time restricted feeding on body weight and metabolic disease risk factors in obese adults
- Antoni et al., 2018 – A pilot feasibility study exploring the effects of a moderate time-restricted feeding intervention on energy intake, adiposity and metabolic physiology in free-living human subjects
- Yet unpublished study by Stegler et al., – Effect of Time-Restricted Eating on Weight, Fat Loss and Cardiometabolic Risk in Adults With Obesity
- Chrononutrition article on Stronger By Science
“I Have a Question!” [57:27]
Today’s questions from our Patreon supporters:
- Lawrence – Is there evidence for avoidance of any of the macronutrients being more important during an overnight and morning fast? For context: I stop eating at 6 pm and don’t eat again until 9 or 10 in the morning. But I do have some cream or half & half in my coffee at 6 am. Is that ‘cranking up’ any metabolic machinery that it would be better not to? Would sugar be worse?
- James – Is there an imagined evolutionary argument for why it is that TRF is beneficial for health? How much of this appears to rest mechanistically on autophagy?
- Kyla – Are there any considerations on how much or how long to engage in a fast or TRE window based on gender?
Quack Asylum [73:35]
- Fasting is the solution to everything, including cancer…
Random Recommendations [86:05]
Alan’s Recommendation: Norse Mythology – Neil Gaiman
Danny’s Recommendation: The Worm at the Core – Sheldon Solomon, Jeff Greenberg & Tom Pyszczynski

